Ovarian Cancer

Published in the September 17 issue of The Journal of Neuroscience, these findings help explain how physical therapy advances recovery, and support the use of rehabilitation therapies that specifically target impaired limbs in people with brain and spinal cord injuries. "After brain and spinal cord injuries, exercise-based physical therapy is the primary rehabilitative strategy in [...]

A team led by Richard Borgens of the School of Veterinary Medicine’s Center for Paralysis Research and Welden School of Biomedical Engineering coated silica nanoparticles with a polymer to target and repair injured guinea pig spinal cords. That research is being published in the October edition of the journal Small. The team then used the [...]

Spinal chord injuries represent a serious and irreversible handicap that is sadly frequent in our society. Because of the permanent break in the nervous connections between the brain and the organs and muscles, such injuries impair their movement inducing atrophy and deterioration while they disturb organic functions. The pioneering studies carried out by Santiago Ramón [...]

Stem cells have two main characteristics: First, they are able to differentiate into all the different cell types that make up their respective tissue – a property called pluripotency. Second, they need to renew themselves in order to be able to supply new specialized tissue cells throughout life. These processes have best been studied in [...]

Their study is published online, Dec. 1, 2008, in the Journal of Clinical Investigation. Small, noncoding RNA molecules known as miRNAs are powerful natural repressors of gene expression. In the study, the miRNA miR-181a was harnessed to segregate expression of genes in immune cells known as T cells at different stages of their development. miR-181a [...]

"We knew going into this study that there was an association between thiazolidinediones and fracture risk, however the magnitude of risk had not been evaluated," said Sonal Singh, M.D., M.P.H., an assistant professor of internal medicine and a co-researcher for the study. "This study shows that these agents double the risk of fractures in women [...]

The researchers, from Purdue University and The Catholic University of America, also have proposed a mechanism for how the motor works. Parts of the motor move in sequence like the pistons in a car’s engine, progressively drawing the genetic material into the virus’s head, or capsid, said Michael Rossmann, Purdue’s Hanley Distinguished Professor of Biological [...]

Osteoporotic fractures represent a growing public health problem in both developed and developing countries, with a projected increasing incidence as the population ages. There are limited data on the long-term risk of death following osteoporotic fracture or a subsequent fracture, according to background information in the article. Dana Bliuc, M.Med., of the Garvan Institute of [...]

Equally important, this study also suggests that at least for some people with asthma and allergies, their problems might be caused by genes that prevent this switch from working properly. Taken together, this information is an important first step toward new medications that address the root causes of allergies, asthma and other similar diseases. "This [...]

Publishing in the current issue of Cell Transplantation (Vol. 18 No.1), a team of Japanese researchers describe their study that demonstrates a way to eliminate the problem of tumor growth by co-transplanting bone marrow stem cells (BMSCs) along with embryonic stem cells. "Our study results suggest that co-transplanting BMSCs induce undifferentiated embryonic stem cells to [...]